A smart dual-responsive nanoplatform for delivery of prochloraz for the control of rice blast disease

Shortening Nano-controlled release formulations present a promising strategy to mitigate pesticide losses and enhance efficiency.In this study, a pH and GSH-responsive nanoplatform using mesoporous organosilica nanoparticles (MONs) as a copyright and poly(tannic acid) (PTA) as capping agent was established for controlling prochloraz (Pro) release.The obtained Pro@MON@PTA was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA).

The results indicate the successful preparation of Pro@MON@PTA nanoparticles, featuring uniform particle size (190 nm), excellent dispersibility, and a prochloraz loading efficiency of 17.2%.Evaluation of contact angle Front Closure Bras and adhesion work demonstrated superior adhesion of MON@PTA to rice leaves compared to MON.

Controlled release studies revealed dual-responsive release properties of Pro@MON@PTA to acid and GSH.Additionally, photostability testing indicated effective ultraviolet light shielding by the copyright, reducing prochloraz degradation under irradiation.Bioassay results indicated equivalent fungicidal activity against Magnaporthe oryzae between Pro@MON@PTA and prochloraz technical and prochloraz EW after a 7-day treatment.

However, in vivo experiments demonstrated that Pro@MON@PTA exhibited superior control efficacy compared to prochloraz EW.These findings suggested that MON@PTA holds significant potential for plant disease management.

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